Absorption refers to which process?

Absorption refers to which process?

• A. Movement of drug from the site of administration to systemic circulation
• B. Metabolism in the liver
• C. Distribution to tissues
• D. Excretion by kidneys

Answer: (A)

Absorption is the entry of a drug into the bloodstream from the site where it was given. It describes the movement of the drug from the administration site through tissues into the systemic circulation, which determines how much becomes available to have an effect (bioavailability). This is distinct from metabolism, which happens mainly in the liver to chemically alter the drug; distribution, which is the drug’s passage from blood into tissues and compartments; and excretion, which removes drug and metabolites from the body. For routes like IV administration, absorption is bypassed because the drug is already in the blood, illustrating how absorption specifically refers to entering the bloodstream from the site of administration. Factors such as route, formulation, solubility, pH, and blood flow influence how well absorption occurs.

Absorption is the entry of a drug into the bloodstream from the site where it was given. It describes the movement of the drug from the administration site through tissues into the systemic circulation, which determines how much becomes available to have an effect (bioavailability). This is distinct from metabolism, which happens mainly in the liver to chemically alter the drug; distribution, which is the drug’s passage from blood into tissues and compartments; and excretion, which removes drug and metabolites from the body. For routes like IV administration, absorption is bypassed because the drug is already in the blood, illustrating how absorption specifically refers to entering the bloodstream from the site of administration. Factors such as route, formulation, solubility, pH, and blood flow influence how well absorption occurs.